In today’s society, alcohol is a common factor associated with many deaths including those related to drinking and driving, alcohol overdose and chronic binge drinking. The purpose of this video is to demonstrate the effects of alcohol on the body from both a physiological and neurological stance. By exploring the various negative consequences of long-term alcohol consumption, we hope to provide viewers with statistics and an analysis to help reduce the number of irresponsible cases/accidents associated with alcohol misuse. In particular this video focuses on the effects of alcohol in relation to the liver, kidneys, and the brain. This video also incorporates alternative methods that can provide people with happiness and pleasure, in hopes to reduce the number of alcohol-related incidents.
This video was made by McMaster students Noah Stancati, Michelle Huynh and Amelinda Firdauzy in collaboration with the McMaster Demystifying Program
Copyright McMaster University, 2020
References:
Abrahao, K. P., Salinas, A. G., & Lovinger, D. M. (2017). Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. Neuron, 96(6), 1223–1238. https://doi.org/10.1016/j.neuron.2017.10.032
Beck, A., Wüstenberg, T., Genauck, A., Wrase, J., Schlagenhauf, F., Smolka, M. N., Mann, K., & Heinz, A. (2012). Effect of Brain Structure, Brain Function, and Brain Connectivity on Relapse in Alcohol-Dependent Patients. Archives of General Psychiatry, 69(8), 842. https://doi.org/10.1001/archgenpsychiatry.2011.2026
Centre for Disease Control and Prevention Facts about moderate drinking | CDC. (2020, January 31). https://www.cdc.gov/alcohol/fact-sheets/moderate-drinking.htm
Criswell, H. E., Ming, Z., Kelm, M. K., & Breese, G. R. (2008). Brain Regional Differences in the Effect of Ethanol on GABA Release from Presynaptic Terminals. Journal of Pharmacology and Experimental Therapeutics, 326(2), 596–603. https://doi.org/10.1124/jpet.107.135418
McClintick, J. N., McBride, W. J., Bell, R. L., Ding, Z.-M., Liu, Y., Xuei, X., & Edenberg, H. J. (2016). Gene Expression Changes in Glutamate and GABA-A Receptors, Neuropeptides, Ion Channels, and Cholesterol Synthesis in the Periaqueductal Gray Following Binge-Like Alcohol Drinking by Adolescent Alcohol-Preferring (P) Rats. Alcoholism: Clinical and Experimental Research, 40(5), 955–968. https://doi.org/10.1111/acer.13056
Olfandis, N.T. (2019). Alcoholic Liver Disease—Liver and Gallbladder Disorders. Merck Manuals Consumer Version. Retrieved December 1, 2020, from https://www.merckmanuals.com/home/liver-and-gallbladder-disorders/alcoholic-liver-disease/alcoholic-liver-disease
Sullivan, E. V., & Pfefferbaum, A. (2009). Neuroimaging of the Wernicke-Korsakoff Syndrome. Alcohol and Alcoholism, 44(2), 155–165. https://doi.org/10.1093/alcalc/agn103
White, S. L., Polkinghorne, K. R., Cass, A., Shaw, J. E., Atkins, R. C., & Chadban, S. J. (2009). Alcohol consumption and 5-year onset of chronic kidney disease: The AusDiab study. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association – European Renal Association, 24(8), 2464–2472. https://doi.org/10.1093/ndt/gfp114
){kind=link}
Comments
Comments are disabled for this post.