My talk will provide an overview and update on psychedelic-assisted treatment of addiction, with a focus on recent work with psilocybin in alcohol use disorder. Alcoholism was the most-studied indication for psychedelic therapy in the 1950s and 1960s. Although the controlled trials of that era had limitations, LSD was shown to lead to clinically significant benefit when the results of these studies were pooled in a meta-analysis many years later. Psilocybin-assisted treatment has recently been shown result in significant improvement in uncontrolled proof-of-concept studies addressing alcohol and nicotine dependence. We are currently conducting a full-scale double-blind randomised controlled trial of psilocybin- assisted treatment of alcohol use disorder. I will discuss the design of this study, experience with study participants, and current hypotheses concerning the possible mechanisms of action of psilocybin-assisted treatment.
Filmed at Breaking Convention 2017 – 4th International Conference on Psychedelic Consciousness University of Greenwich London, June 30th-July 2nd 2017
www.breakingconvention.co.uk
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